Publications

Birtamimab

PRASINEZUMAB

PRX004

OTHER

  • Vascular alterations in PDAPP mice following anti-Aβ immunotherapy: Implications for amyloid-related imaging abnormalities (ARIA)

    Vascular alterations in PDAPP mice following anti-Aβ immunotherapy: Implications for amyloid-related imaging abnormalities (ARIA)W. Zago, S. Schroeter, T. Guido, K. Khan, P. Seubert, T. Yednock, D. Schenk, K.M. Gregg, D. Games, F. Bard, G.G. Kinney
    Alzheimers Dementia 9, S105–S115 (2013)

  • Neutralization of soluble synaptotoxic Aß species by antibodies is epitope specific

    Neutralization of soluble synaptotoxic Aß species by antibodies is epitope specificW. Zago, M. Buttini, T.A. Comery, C. Nishioka, P. Seubert, D. Games, F. Bard, D. Schenk, G.G. Kinney
    Journal of Neuroscience, 32:2696-2702 (2012)

  • Sustained levels of antibodies against Aß in amyloid-rich regions of the CNS following intravenous dosing in human APP transgenic mice

    Sustained levels of antibodies against Aß in amyloid-rich regions of the CNS following intravenous dosing in human APP transgenic miceF. Bard, M. Fox, S. Friedrich, P. Seubert, D. Schenk, G.G. Kinney, T. Yednock
    Exp Neurol., 238:38-43 (2012)

  • Structural Correlates of Antibodies Associated with Acute Reversal of Amyloid β-related Behavioral Deficits in a Mouse Model of Alzheimer Disease

    Structural Correlates of Antibodies Associated with Acute Reversal of Amyloid β-related Behavioral Deficits in a Mouse Model of Alzheimer DiseaseG. Basi, H. Feinberg, F. Oshidari, J. Anderson, R. Barbour, J. Baker, T.A. Comery, L. Diep, D. Gill, K. Johnson-Wood, A. Goel, K. Grantcharova, M. Lee, J. Li, A. Partridge, I. Griswold-Prenner, N. Piot, D. Walker, A. Widom, M.N. Pangalos, P. Seubert, J.S. Jacobsen, D. Schenk, W.I. Weis
    Journal of Biological Chemistry 285(5):3417-3427 (2010)

  • Effects of α-Synuclein Immunization in a Mouse Model of Parkinson’s Disease

    Effects of α-Synuclein Immunization in a Mouse Model of Parkinson’s DiseaseE. Masliah, E. Rockenstein, A. Adame, M. Alford, L. Crews, M. Hashimoto, P. Seubert, M. Lee, J. Goldstein, T. Chilcote, D. Games, D. Schenk
    Neuron 46, 857-868 (2005)

  • Aβ42 Immunization in Alzheimer’s Disease Generates Aβ N-Terminal Antibodies

    Aβ42 Immunization in Alzheimer’s Disease Generates Aβ N-Terminal AntibodiesM. Lee, F. Bard, K. Johnson-Wood, C. Lee, K. Hu, S. Griffith, R. Black, D. Schenk, P. Seubert
    Ann. Neurol. 58, 430-435 (2005)

  • Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

    Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouseD. Schenk, R. Barbour, W. Dunn, G. Gordon, H. Grajeda, T. Guido, K. Hu, J. Huang, K. Johnson-Wood, K. Khan, D. Kholodenko, M. Lee, Z. Liao, I. Lieberburg, R. Motter, L. Mutter, F. Soriano, G. Shopp, N. Vazquez, C. Vendevert, S. Walker, M. Wogulis, T. Yednock, D. Games, P. Seubert
    Nature, 400, 173-177 (1999)