Culture & Careers

Prothena’s success is driven by our people. We are dedicated to attracting individuals who share our vision to improve human health by putting patients first.

But it’s not just about what we do at Prothena, it’s how we do it. That’s why we hire creative and courageous individuals who support one another and are not afraid to try new ideas. Our culture reflects our values which are brought to life every day by the following characteristics:


Our shared humanity drives a passionate and unwavering commitment to apply high scientific rigor toward developing innovative new therapies for patients. We have ambitious goals and take every aspect of our mission seriously, while enjoying the journey. Our values connect us – you will see and feel them come to life in all we do – together.


Patients come first and we’re in this together. Our environment is collaborative and we measure success through our collective accomplishments.


Transformational innovation leads to novel treatments. “Tried-and-true” won’t produce breakthroughs for patients – a pioneering spirit, willingness to accept certain risks and to try new approaches. Each Prothenian and functional team is expected to bring their heart, experience and trust on our journey.


We value and encourage a creative approach across all aspects of our work. We challenge ourselves and each other to think beyond what is known and approach our work through a lens of continuous improvement.


Humor and heart allow us to tackle the seriousness of our work. Excellence and fun are not at odds – we love what we do and enjoy the journey.

Cutting-edge science is what we do.

Our scientific legacy includes significant discoveries that have fundamentally advanced the understanding of neurobiology. “Tried-and-true” simply doesn’t produce breakthroughs. We are driven to create life-changing medicines that are truly disease modifying based on innovative and rigorous science.

Our passion is the patient.

We’re working to develop new medicines to fundamentally alter the course of progressive diseases.

We’re in it for the long haul.

Our expertise and experience serve as a solid foundation for our ambitious goals. We believe in championing promising new approaches, and are driven to succeed.

Collaboration is key.

We are transforming the neurotherapeutic R&D paradigm. No one can do it alone. Collaboration is at the root of all we do, starting with how we communicate and work together.

We embrace creativity and risk-taking.

We are at the crossroads of new possibilities in neuroscience – to search out and seize upon emergent innovative therapies. Advances can only come from taking risk and forging into uncharted scientific territory. We embrace what innovation requires.

The team comes first.

Our model uniquely builds teams and promotes shared learning across our portfolio – our core team serves as the model for platform-wide and company-wide respect and support. We’re in this together and we value the contributions everyone makes toward the common goal of helping patients.

We love what we do.

We are dedicated to our mission, and celebrate our successes—the big ones, the little ones, and everything in between. We invite you to join us in creating successes we can all celebrate.


Prothena’s future success lies in the ability to attract and retain great employees. We recognize strong individual performance, and reward it accordingly with market-competitive salaries and cash and equity incentive compensation plans. In addition, our comprehensive benefits program is designed to meet the personal needs of our employees by offering choice and flexibility.

We offer highly competitive benefits across health & wellness, financial well-being and work/life balance categories, and invite you to find out more about current opportunities.

Click here to access machine-readable files that are made available in response to the federal Transparency in Coverage Rule and include negotiated service rates and out-of-network allowed amounts between health plans and healthcare providers. The machine-readable files are formatted to allow researchers, regulators, and application developers to access and analyze data more easily.

A woman smiling as she interviews for an open position at Prothena


Please explore current career opportunities, connect with us via LinkedIn, or contact us directly at

Prothena is an Equal Opportunity Employer and does not discriminate on the basis of actual or perceived race, color, national origin, ancestry, sex, gender, gender identity, pregnancy, childbirth or related medical condition, religious creed, physical disability, mental disability, age, medical condition, marital status, sexual orientation, or any other characteristic protected by federal, state or local law.