TRAN B. NGUYEN

Chief Financial Officer and Chief Strategy Officer

Mr. Nguyen has served as Prothena’s Chief Financial Officer since 2013 and served as Chief Operating Officer from 2018 through September 2021. He has over 20 years of finance experience in the biotechnology, banking, and private equity industries. Prior to joining Prothena, Mr. Nguyen held management positions at Somaxon Pharmaceuticals, Inc. and was its Chief Financial Officer until its sale in 2013. He was previously Vice President, Chief Financial Officer at Metabasis Therapeutics, Inc. until its sale in 2010. Mr. Nguyen currently serves on the board of Rain Therapeutics Inc., a public late-stage clinical precision oncology company. Mr. Nguyen earned his B.A. in Economics and Psychology from Claremont McKenna College and his M.B.A. from the Anderson School of Management at the University of California, Los Angeles.